Structure analysis

Structure of HLA-A*0201 complexed with peptide Md3-C9 derived from a clustering region of restricted cytotoxic T lymphocyte epitope from SARS-CoV M protein

X-ray diffraction
2.6Å resolution
Assembly composition:
hetero trimer (preferred)
Entry contents: 3 distinct polypeptide molecules

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero trimer
Accessible surface area: 18941.31 Å2
Buried surface area: 4221.76 Å2
Dissociation area: 1,274.15 Å2
Dissociation energy (ΔGdiss): 5.44 kcal/mol
Dissociation entropy (TΔSdiss): 12.08 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-157825

Macromolecules

PDBe-KB: UniProt Coverage View: Q53Z42  
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Chain: B
Length: 100 amino acids
Theoretical weight: 11.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Pfam: Immunoglobulin C1-set domain
InterPro:
CATH: Immunoglobulins
PDBe-KB: UniProt Coverage View: P61769  
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Chain: C
Length: 9 amino acids
Theoretical weight: 906 Da
Source organism: SARS coronavirus TJF
Expression system: Not provided
UniProt:
  • Canonical: P59596 (Residues: 61-69; Coverage: 4%)
Gene names: 5, M
PDBe-KB: UniProt Coverage View: P59596  
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