Function and Biology

Crystal structure of human Survivin bound to histone H3 phosphorylated on threonine-3.

Source organism: Homo sapiens
Biochemical function: protein-folding chaperone binding
Biological process: positive regulation of mitotic cytokinesis
Cellular component: survivin complex

Sequence family

Pfam Protein family (Pfam)
PF00653
Domain description: Inhibitor of Apoptosis domain
Occurring in:
  1. Baculoviral IAP repeat-containing protein 5
The deposited structure of PDB entry 3uec contains 1 copy of Pfam domain PF00653 (Inhibitor of Apoptosis domain) in Baculoviral IAP repeat-containing protein 5. Showing 1 copy in chain A.

InterPro InterPro annotation
IPR001370
Domain description: BIR repeat
Occurring in:
  1. Baculoviral IAP repeat-containing protein 5

Structure domain

CATH CATH domain
1.10.1170.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A
Homology: Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A
Occurring in:
  1. Baculoviral IAP repeat-containing protein 5
The deposited structure of PDB entry 3uec contains 1 copy of CATH domain 1.10.1170.10 (Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A) in Baculoviral IAP repeat-containing protein 5. Showing 1 copy in chain A.