Function and Biology

Crystal structure of a probable glycerol dehydrogenase from Sinorhizobium meliloti 1021

Source organism: Sinorhizobium meliloti
Biochemical function: metal ion binding
Biological process: not assigned
Cellular component: not assigned

EC 1.1.1.6: Glycerol dehydrogenase

Reaction catalysed:
Glycerol + NAD(+) = glycerone + NADH
Systematic name:
Glycerol:NAD(+) 2-oxidoreductase
Alternative Name(s):
  • Glycerin dehydrogenase
  • NAD-linked glycerol dehydrogenase

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00465
Domain description: Iron-containing alcohol dehydrogenase
Occurring in:
  1. Glycerol dehydrogenase
The deposited structure of PDB entry 3uhj contains 8 copies of Pfam domain PF00465 (Iron-containing alcohol dehydrogenase ) in Glycerol dehydrogenase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR016205
Domain description: Glycerol dehydrogenase
Occurring in:
  1. Glycerol dehydrogenase
IPR018211
Domain description: Alcohol dehydrogenase, iron-type, conserved site
Occurring in:
  1. Glycerol dehydrogenase
IPR001670
Domain description: Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA
Occurring in:
  1. Glycerol dehydrogenase

Structure domains

CATH CATH domains
1.20.1090.10
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Dehydroquinate synthase-like, alpha domain
Homology: Dehydroquinate synthase-like - alpha domain
Occurring in:
  1. Glycerol dehydrogenase
The deposited structure of PDB entry 3uhj contains 8 copies of CATH domain 1.20.1090.10 (Dehydroquinate synthase-like, alpha domain) in Glycerol dehydrogenase. Showing 1 copy in chain A.
3.40.50.1970
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: Rossmann fold
Occurring in:
  1. Glycerol dehydrogenase
The deposited structure of PDB entry 3uhj contains 8 copies of CATH domain 3.40.50.1970 (Rossmann fold) in Glycerol dehydrogenase. Showing 1 copy in chain A.