› › Bifunctional dihydrofolate reductase-thymidylate synthase

Bifunctional dihydrofolate reductase-thymidylate synthase in PDB entry 3um5, assembly 1, front view.
Bifunctional dihydrofolate reductase-thymidylate synthase in PDB entry 3um5, assembly 1, side view.
Bifunctional dihydrofolate reductase-thymidylate synthase in PDB entry 3um5, assembly 1, top view.
Chains: A, B
Length: 608 amino acids
Theoretical weight: 71.87 KDa
Source organism: Plasmodium falciparum
Expression system: Escherichia coli
UniProt:
  • Canonical: A7UD81 (Residues: 1-608; Coverage: 100%)
Gene names: DHFR-TS, dhfr-ts
FASTA Sequence
>pdb|3um5|A B
MMEQVCDVFDIYAICVCCKVESKNEGKKNEVFNNYTFRGLGNKGVLPWKCNSLDMKYFCAVTTYVNESKYEKLKYKRCKYLNKETVDNVNDMPNSKKLQNVVVMGRTTWESIPKKFKPLSNRINVILSRTLKKEDFDEDVYIINKVEDLIVLLGKLNYYKCFIIGGSVVYQEFLEKKLIKKIYFTRINSTYECDVFFPEINENEYQIISVSDVYTSNNTTLDFIIYKKTNNKMLNEQNCIKGEEKNNDMPLKNDDKDTCHMKKLTEFYKNVDKYKINYENDDDDEEEDDFVYFNFNKEKEEKNKNSIHPNDFQIYNSLKYKYHPEYQYLNIIYDIMMNGNKQSDRTGVGVLSKFGYIMKFDLSQYFPLLTTKKLFLRGIIEELLWFIRGETNGNTLLNKNVRIWEANGTREFLDNRKLFHREVNDLGPIYGFQWRHFGAEYTNMYDNYENKGVDQLKNIINLIKNDPTSRRILLCAWNVKDLDQMALPPCHILCQFYVFDGKLSCIMYQRSCDLGLGVPFNIASYSIFTHMIAQVCNLQPAQFIHVLGNAHVYNNHIDSLKIQLNRIPYPFPTLKLNPDIKNIEDFTISDFTIQNYVHHEKISMDMAA
PDBe-KB: UniProt Coverage View: A7UD81  

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