› › Function and Biology

Crystal structure of the electron transfer complex of cytochrome p450cam with putidaredoxin

Source organism: Pseudomonas putida
Biochemical function: metal ion binding
Biological process: P450-containing electron transport chain
Cellular component: cytosol

Quick links

EC 1.14.15.1: Camphor 5-monooxygenase

Reaction catalysed:
(+)-camphor + reduced putidaredoxin + O(2) = (+)-exo-5-hydroxycamphor + oxidized putidaredoxin + H(2)O
Systematic name:
(+)-camphor,reduced putidaredoxin:oxygen oxidoreductase (5-hydroxylating)
Alternative Name(s):
  • 2-bornanone 5-exo-hydroxylase
  • Bornanone 5-exo-hydroxylase
  • Camphor 5-exo-hydroxylase
  • Camphor 5-exo-methylene hydroxylase
  • Camphor 5-exohydroxylase
  • Camphor hydroxylase
  • Camphor methylene hydroxylase
  • Cytochrome p450-cam
  • D-camphor monooxygenase
  • D-camphor-exo-hydroxylase
  • Methylene hydroxylase
  • Methylene monooxygenase

GO terms

Sequence families

Pfam Protein families (Pfam)
PF00111
Domain description: 2Fe-2S iron-sulfur cluster binding domain
Occurring in:
  1. Putidaredoxin
The deposited structure of PDB entry 3w9c contains 1 copy of Pfam domain PF00111 (2Fe-2S iron-sulfur cluster binding domain) in Putidaredoxin. Showing 1 copy in chain B.

PF00067
Domain description: Cytochrome P450
Occurring in:
  1. Camphor 5-monooxygenase
The deposited structure of PDB entry 3w9c contains 1 copy of Pfam domain PF00067 (Cytochrome P450) in Camphor 5-monooxygenase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR002397
Domain description: Cytochrome P450, B-class
Occurring in:
  1. Camphor 5-monooxygenase
IPR001128
Domain description: Cytochrome P450
Occurring in:
  1. Camphor 5-monooxygenase
IPR001055
Domain description: Adrenodoxin-like
Occurring in:
  1. Putidaredoxin
IPR001041
Domain description: 2Fe-2S ferredoxin-type iron-sulfur binding domain
Occurring in:
  1. Putidaredoxin
IPR036396
Domain description: Cytochrome P450 superfamily
Occurring in:
  1. Camphor 5-monooxygenase
IPR018298
Domain description: Adrenodoxin, iron-sulphur binding site
Occurring in:
  1. Putidaredoxin
IPR036010
Domain description: 2Fe-2S ferredoxin-like superfamily
Occurring in:
  1. Putidaredoxin
IPR012675
Domain description: Beta-grasp domain superfamily
Occurring in:
  1. Putidaredoxin
IPR017972
Domain description: Cytochrome P450, conserved site
Occurring in:
  1. Camphor 5-monooxygenase

Structure domains

CATH CATH domains
3.10.20.30
Class: Alpha Beta
Architecture: Roll
Topology: Ubiquitin-like (UB roll)
Homology: Ubiquitin-like (UB roll)
Occurring in:
  1. Putidaredoxin
The deposited structure of PDB entry 3w9c contains 1 copy of CATH domain 3.10.20.30 (Ubiquitin-like (UB roll)) in Putidaredoxin. Showing 1 copy in chain B.
1.10.630.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Cytochrome p450
Homology: Cytochrome P450
Occurring in:
  1. Camphor 5-monooxygenase
The deposited structure of PDB entry 3w9c contains 1 copy of CATH domain 1.10.630.10 (Cytochrome p450) in Camphor 5-monooxygenase. Showing 1 copy in chain A.

Quick links