Structure analysis

Cryo-EM structures of two intermediates provide insight into adenovirus assembly and disassembly

Electron Microscopy
4.5Å resolution
Source organism: Bovine adenovirus 3
Assembly composition:
hetero 1080-mer (preferred)
Entry contents: 4 distinct polypeptide molecules

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero 1080-mer
PDBe Complex ID: PDB-CPX-136683

Macromolecules

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Chain: M
Length: 482 amino acids
Theoretical weight: 55.14 KDa
Source organism: Bovine adenovirus 3
InterPro: Adenovirus penton base protein

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Chains: N, O, P, Q
Length: 125 amino acids
Theoretical weight: 13.72 KDa
Source organism: Bovine adenovirus 3
UniProt:
  • Canonical: Q64845 (Residues: 1-125; Coverage: 100%)
Pfam: Adenovirus hexon-associated protein (IX)
InterPro: Hexon-associated protein IX

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Chain: R
Length: 216 amino acids
Theoretical weight: 23.75 KDa
Source organism: Bovine adenovirus 3
InterPro: Pre-hexon-linking protein VIII

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