› › Structure analysis

P38ALPHA MAP KINASE BOUND TO CMPD 29

X-ray diffraction
2.5Å resolution
PDB entry 4aac coloured by chain, front view.
PDB entry 4aac coloured by chain, side view.
PDB entry 4aac coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Mitogen-activated protein kinase 14
hide full assembly name
Multimeric state: monomeric
Accessible surface area: 16906.35 Å2
Buried surface area: 141.27 Å2
Dissociation area: 70.63 Å2
Dissociation energy (ΔGdiss): 13.48 kcal/mol
Dissociation entropy (TΔSdiss): -0.82 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-172487

Macromolecules

Mitogen-activated protein kinase 14
Chain: A
Length: 365 amino acids
Theoretical weight: 42.04 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q16539 (Residues: 2-360; Coverage: 100%)
Gene names: CSBP, CSBP1, CSBP2, CSPB1, MAPK14, MXI2, SAPK2A
Pfam: Protein kinase domain
InterPro:
CATH:
Mitogen-activated protein kinase 14 in PDB entry 4aac, assembly 1, front view.
Mitogen-activated protein kinase 14 in PDB entry 4aac, assembly 1, side view.
Mitogen-activated protein kinase 14 in PDB entry 4aac, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links