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Crystal Structure of Epithelial Adhesin 1 A domain (Epa1A) from Candida glabrata in complex with Galb1-3Glc

X-ray diffraction
1.5Å resolution
PDB entry 4af9 coloured by chain, front view.
PDB entry 4af9 coloured by chain, side view.
PDB entry 4af9 coloured by chain, top view.
Source organism: [Candida] glabrata
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: PA14 domain-containing protein
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Multimeric state: homo dimer
Accessible surface area: 19822.35 Å2
Buried surface area: 5531.42 Å2
Dissociation area: 784.64 Å2
Dissociation energy (ΔGdiss): -1.12 kcal/mol
Dissociation entropy (TΔSdiss): 12.89 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-180455

Macromolecules

PA14 domain-containing protein
Chain: A
Length: 262 amino acids
Theoretical weight: 29.44 KDa
Source organism: [Candida] glabrata
Expression system: Escherichia coli B
UniProt:
  • Canonical: Q6VBJ0 (Residues: 31-271; Coverage: 24%)
Gene name: EPA1
Pfam: GLEYA domain
InterPro:
CATH: Jelly Rolls
PA14 domain-containing protein in PDB entry 4af9, assembly 1, front view.
PA14 domain-containing protein in PDB entry 4af9, assembly 1, side view.
PA14 domain-containing protein in PDB entry 4af9, assembly 1, top view.
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