› 4akv

X-ray diffraction
2.65Å resolution

Crystal structure of human sorting nexin 33 (SNX33)

Released:
DOI: 10.2210/pdb4akv/pdb
PDB entry 4akv coloured by chain, front view.
PDB entry 4akv coloured by chain, side view.
PDB entry 4akv coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Oberholzer A, Froese DS, Krojer T, Shrestha L, Filippakopoulos P, Muniz JRC, von Delft F, Arrowsmith C, Weigelt J, Edwards A, Bountra C, Yue WW

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186730 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sorting nexin-33 Chains: A, B
Molecule details ›
Chains: A, B
Length: 386 amino acids
Theoretical weight: 45.37 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8WV41 (Residues: 212-574; Coverage: 63%)
Gene names: SH3PX3, SH3PXD3C, SNX30, SNX33
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand SO4 6 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P21212
Unit cell:
a: 68.65Å b: 216.21Å c: 58.2Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.213 0.21 0.27
Expression system: Escherichia coli BL21(DE3)

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