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Crystal structure of human sorting nexin 33 (SNX33)

X-ray diffraction
2.651Å resolution
PDB entry 4akv coloured by chain, front view.
PDB entry 4akv coloured by chain, side view.
PDB entry 4akv coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Sorting nexin-33
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Multimeric state: homo dimer
Accessible surface area: 32541.59 Å2
Buried surface area: 7004.67 Å2
Dissociation area: 2,925.67 Å2
Dissociation energy (ΔGdiss): 48.94 kcal/mol
Dissociation entropy (TΔSdiss): 14.76 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-186730

Macromolecules

Sorting nexin-33
Chains: A, B
Length: 386 amino acids
Theoretical weight: 45.37 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8WV41 (Residues: 212-574; Coverage: 63%)
Gene names: SH3PX3, SH3PXD3C, SNX30, SNX33
Pfam:
InterPro:
CATH:
Sorting nexin-33 in PDB entry 4akv, assembly 1, front view.
Sorting nexin-33 in PDB entry 4akv, assembly 1, side view.
Sorting nexin-33 in PDB entry 4akv, assembly 1, top view.
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