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human Aquaporin

X-ray diffraction
3.28Å resolution
PDB entry 4csk coloured by chain, front view.
PDB entry 4csk coloured by chain, side view.
PDB entry 4csk coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo tetramer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Aquaporin-1
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Multimeric state: homo tetramer
Accessible surface area: 33201.86 Å2
Buried surface area: 13467.57 Å2
Dissociation area: 6,733.78 Å2
Dissociation energy (ΔGdiss): 84.47 kcal/mol
Dissociation entropy (TΔSdiss): 40.92 kcal/mol
Symmetry number: 4
PDBe Complex ID: PDB-CPX-151591

Macromolecules

Aquaporin-1
Chain: A
Length: 292 amino acids
Theoretical weight: 31.17 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P29972 (Residues: 1-269; Coverage: 100%)
Gene names: AQP1, CHIP28
Pfam: Major intrinsic protein
InterPro:
CATH: Glycerol uptake facilitator protein.
Aquaporin-1 in PDB entry 4csk, assembly 1, front view.
Aquaporin-1 in PDB entry 4csk, assembly 1, side view.
Aquaporin-1 in PDB entry 4csk, assembly 1, top view.
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