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Structure of the carboxy-terminal domain of the turkey type 3 siadenovirus fibre, virulent form

X-ray diffraction
2.3Å resolution
PDB entry 4cw8 coloured by chain, front view.
PDB entry 4cw8 coloured by chain, side view.
PDB entry 4cw8 coloured by chain, top view.
Source organism: Turkey adenovirus 3
Assembly composition:
homo trimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Fiber knob domain
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Multimeric state: homo trimer
Accessible surface area: 16590.92 Å2
Buried surface area: 8106.16 Å2
Dissociation area: 3,572.19 Å2
Dissociation energy (ΔGdiss): 38.23 kcal/mol
Dissociation entropy (TΔSdiss): 24.93 kcal/mol
Symmetry number: 3
PDBe Complex ID: PDB-CPX-170930

Macromolecules

Fiber knob domain
Chain: A
Length: 190 amino acids
Theoretical weight: 20.84 KDa
Source organism: Turkey adenovirus 3
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q0GF90 (Residues: 12-165; Coverage: 93%)
Pfam: Turkey Adenovirus 3 Fibre protein-like, head domain
InterPro: Aldolase-type TIM barrel
CATH: Adenovirus Type 5 Fiber Protein (Receptor Binding Domain)
Fiber knob domain in PDB entry 4cw8, assembly 1, front view.
Fiber knob domain in PDB entry 4cw8, assembly 1, side view.
Fiber knob domain in PDB entry 4cw8, assembly 1, top view.
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