Structure analysis

Complex of Neurospora crassa PAN2 (WD40-CS1) with PAN3 (pseudokinase and C-term)

X-ray diffraction
3.4Å resolution
Source organism: Neurospora crassa
Assembly composition:
hetero tetramer (preferred)
Entry contents: 2 distinct polypeptide molecules

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero tetramer
Accessible surface area: 63707.51 Å2
Buried surface area: 12225.08 Å2
Dissociation area: 1,394.05 Å2
Dissociation energy (ΔGdiss): -2.19 kcal/mol
Dissociation entropy (TΔSdiss): 28.04 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-143024

Macromolecules

Chains: A, C
Length: 354 amino acids
Theoretical weight: 39.52 KDa
Source organism: Neurospora crassa
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P0C581 (Residues: 1-351; Coverage: 27%)
Gene names: NCU04792, NCU10733, pan2, par-1
Pfam: PAN2 N-terminal
InterPro:
CATH: YVTN repeat-like/Quinoprotein amine dehydrogenase

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Chains: B, D
Length: 429 amino acids
Theoretical weight: 49.27 KDa
Source organism: Neurospora crassa
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q7SDP4 (Residues: 234-656; Coverage: 65%)
Gene names: NCU01929, pan3, par-2
Pfam: Pan3 Pseudokinase domain
InterPro:
CATH:

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