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Crystal structure of the ATP-gated P2X4 ion channel in the ATP-bound, open state at 2.8 Angstroms

Source organism: Danio rerio
Biochemical function: ATP binding
Biological process: monoatomic cation transmembrane transport
Cellular component: membrane

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GO terms

Sequence family

Pfam Protein family (Pfam)
PF00864
Domain description: ATP P2X receptor
Occurring in:
  1. P2X purinoceptor 4a
The deposited structure of PDB entry 4dw1 contains 1 copy of Pfam domain PF00864 (ATP P2X receptor) in P2X purinoceptor 4a. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001429
Domain description: P2X purinoreceptor
Occurring in:
  1. P2X purinoceptor 4a
IPR003047
Domain description: P2X4 purinoceptor
Occurring in:
  1. P2X purinoceptor 4a
IPR027309
Domain description: P2X purinoreceptor extracellular domain superfamily
Occurring in:
  1. P2X purinoceptor 4a

Structure domains

CATH CATH domains
1.10.287.940
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Helix Hairpins
Homology: atp-gated p2x4 ion channel
Occurring in:
  1. P2X purinoceptor 4a
The deposited structure of PDB entry 4dw1 contains 1 copy of CATH domain 1.10.287.940 (Helix Hairpins) in P2X purinoceptor 4a. Showing 1 copy in chain A.
2.60.490.10
Class: Mainly Beta
Architecture: Sandwich
Topology: atp-gated p2x4 ion channel fold
Homology: atp-gated p2x4 ion channel domain
Occurring in:
  1. P2X purinoceptor 4a
The deposited structure of PDB entry 4dw1 contains 1 copy of CATH domain 2.60.490.10 (atp-gated p2x4 ion channel fold) in P2X purinoceptor 4a. Showing 1 copy in chain A.

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