Assemblies
Assembly Name:
Acetylcholinesterase and Fasciculin-2
Multimeric state:
hetero dimer
Accessible surface area:
22952.64 Å2
Buried surface area:
3907.59 Å2
Dissociation area:
1,118.62
Å2
Dissociation energy (ΔGdiss):
3.76
kcal/mol
Dissociation entropy (TΔSdiss):
11.06
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-142974
Macromolecules
Chain: A
Length: 542 amino acids
Theoretical weight: 59.45 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Pfam: Carboxylesterase family
InterPro:
Length: 542 amino acids
Theoretical weight: 59.45 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
P22303 (Residues: 33-574; Coverage: 93%)
Pfam: Carboxylesterase family
InterPro:
- Alpha/Beta hydrolase fold
- Carboxylesterase, type B
- Cholinesterase
- Carboxylesterase type B, conserved site
- Carboxylesterase type B, active site
PDBe-KB: UniProt Coverage View:
P22303
P22303
Chains
Domains
Secondary structure
Flexibility predictions
Early folding residue predictions
Ligand binding sites
Interaction interfaces
Chain: B
Length: 61 amino acids
Theoretical weight: 6.77 KDa
Source organism: Dendroaspis angusticeps
UniProt:
InterPro:
CATH: CD59
Length: 61 amino acids
Theoretical weight: 6.77 KDa
Source organism: Dendroaspis angusticeps
UniProt:
- Canonical: P0C1Z0 (Residues: 1-61; Coverage: 100%)
InterPro:
CATH: CD59
PDBe-KB: UniProt Coverage View:
P0C1Z0
P0C1Z0
Chains
Domains
Secondary structure
Flexibility predictions
Early folding residue predictions
Interaction interfaces