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A subtype N10 neuraminidase-like protein of A/little yellow-shouldered bat/Guatemala/164/2009

X-ray diffraction
1.95Å resolution
PDB entry 4gdi coloured by chain, front view.
PDB entry 4gdi coloured by chain, side view.
PDB entry 4gdi coloured by chain, top view.
Source organism: Influenza A virus (A/little yellow-shouldered bat/Guatemala/164/2009(H17N10))
Assembly composition:
homo tetramer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Neuraminidase
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Multimeric state: homo tetramer
Accessible surface area: 49782.12 Å2
Buried surface area: 23266.89 Å2
Dissociation area: 6,428.11 Å2
Dissociation energy (ΔGdiss): 51.95 kcal/mol
Dissociation entropy (TΔSdiss): 44.22 kcal/mol
Symmetry number: 4
PDBe Complex ID: PDB-CPX-124812
Assembly 2
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Assembly Name: Neuraminidase
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Multimeric state: homo tetramer
Accessible surface area: 50711.58 Å2
Buried surface area: 23197.83 Å2
Dissociation area: 6,908.93 Å2
Dissociation energy (ΔGdiss): 38.9 kcal/mol
Dissociation entropy (TΔSdiss): 44.37 kcal/mol
Symmetry number: 4
PDBe Complex ID: PDB-CPX-124812
Assembly 3
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Assembly Name: Neuraminidase
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Multimeric state: homo tetramer
Accessible surface area: 52195.69 Å2
Buried surface area: 26691.85 Å2
Dissociation area: 6,440.63 Å2
Dissociation energy (ΔGdiss): 54.84 kcal/mol
Dissociation entropy (TΔSdiss): 44.37 kcal/mol
Symmetry number: 4
PDBe Complex ID: PDB-CPX-124812

Macromolecules

Neuraminidase
Chains: A, B, C, D, E, F
Length: 373 amino acids
Theoretical weight: 41.59 KDa
Source organism: Influenza A virus (A/little yellow-shouldered bat/Guatemala/164/2009(H17N10))
Expression system: Trichoplusia ni
UniProt:
  • Canonical: H6QM85 (Residues: 75-442; Coverage: 83%)
Gene name: NA
Pfam: Neuraminidase
InterPro:
CATH: Neuraminidase
Neuraminidase in PDB entry 4gdi, assembly 1, front view.
Neuraminidase in PDB entry 4gdi, assembly 1, side view.
Neuraminidase in PDB entry 4gdi, assembly 1, top view.
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