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Structure of a putative acyl-CoA dehydrogenase from Mycobacterium abscessus

X-ray diffraction
1.8Å resolution
PDB entry 4hr3 coloured by chain, front view.
PDB entry 4hr3 coloured by chain, side view.
PDB entry 4hr3 coloured by chain, top view.
Source organism: Mycobacteroides abscessus ATCC 19977
Assembly composition:
homo tetramer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Acyl-CoA dehydrogenase
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Multimeric state: homo tetramer
Accessible surface area: 55591.84 Å2
Buried surface area: 24052.25 Å2
Dissociation area: 3,810.05 Å2
Dissociation energy (ΔGdiss): 55.06 kcal/mol
Dissociation entropy (TΔSdiss): 15.98 kcal/mol
Symmetry number: 4
PDBe Complex ID: PDB-CPX-109349

Macromolecules

Acyl-CoA dehydrogenase
Chain: A
Length: 415 amino acids
Theoretical weight: 44.53 KDa
Source organism: Mycobacteroides abscessus ATCC 19977
Expression system: Escherichia coli
UniProt:
  • Canonical: B1MFF5 (Residues: 1-411; Coverage: 100%)
Gene name: MAB_0255
Pfam:
InterPro:
CATH:
Acyl-CoA dehydrogenase in PDB entry 4hr3, assembly 1, front view.
Acyl-CoA dehydrogenase in PDB entry 4hr3, assembly 1, side view.
Acyl-CoA dehydrogenase in PDB entry 4hr3, assembly 1, top view.
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