Structure analysis

Crystal structure and mechanism of activation of TBK1

X-ray diffraction
3.065Å resolution
Source organism: Homo sapiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: homo dimer
Accessible surface area: 62360.13 Å2
Buried surface area: 4059.87 Å2
Dissociation area: 2,029.93 Å2
Dissociation energy (ΔGdiss): -2.9 kcal/mol
Dissociation entropy (TΔSdiss): 16.04 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-193743

Macromolecules

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