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Bacterially expressed Titin Kinase

X-ray diffraction
2.06Å resolution
PDB entry 4jnw coloured by chain, front view.
PDB entry 4jnw coloured by chain, side view.
PDB entry 4jnw coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1
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Assembly Name: Titin
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Multimeric state: monomeric
Accessible surface area: 15034.04 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-186809
Assembly 2 (preferred)
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Assembly Name: Titin
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Multimeric state: monomeric
Accessible surface area: 15286.43 Å2
Buried surface area: 404.04 Å2
Dissociation area: 91.63 Å2
Dissociation energy (ΔGdiss): -1.78 kcal/mol
Dissociation entropy (TΔSdiss): 1.03 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-186809

Macromolecules

Titin
Chains: A, B
Length: 324 amino acids
Theoretical weight: 37.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8WZ42 (Residues: 32172-32492; Coverage: 1%)
Gene name: TTN
Pfam: Protein kinase domain
InterPro:
CATH:
Titin in PDB entry 4jnw, assembly 2, front view.
Titin in PDB entry 4jnw, assembly 2, side view.
Titin in PDB entry 4jnw, assembly 2, top view.
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