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Human IkB kinase beta

X-ray diffraction
2.83Å resolution
PDB entry 4kik coloured by chain, front view.
PDB entry 4kik coloured by chain, side view.
PDB entry 4kik coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Inhibitor of nuclear factor kappa-B kinase subunit beta
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Multimeric state: hetero dimer
Accessible surface area: 63384.87 Å2
Buried surface area: 4888.12 Å2
Dissociation area: 1,569.59 Å2
Dissociation energy (ΔGdiss): 13.38 kcal/mol
Dissociation entropy (TΔSdiss): 15.84 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-127197

Macromolecules

Inhibitor of nuclear factor kappa-B kinase subunit beta
Chain: A
Length: 677 amino acids
Theoretical weight: 78.25 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: O14920 (Residues: 2-664; Coverage: 88%)
Gene names: IKBKB, IKKB
Pfam:
InterPro:
CATH:
Inhibitor of nuclear factor kappa-B kinase subunit beta in PDB entry 4kik, assembly 1, front view.
Inhibitor of nuclear factor kappa-B kinase subunit beta in PDB entry 4kik, assembly 1, side view.
Inhibitor of nuclear factor kappa-B kinase subunit beta in PDB entry 4kik, assembly 1, top view.
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Inhibitor of nuclear factor kappa-B kinase subunit beta
Chain: B
Length: 677 amino acids
Theoretical weight: 78.33 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: O14920 (Residues: 2-664; Coverage: 88%)
Gene names: IKBKB, IKKB
Pfam:
InterPro:
CATH:
Inhibitor of nuclear factor kappa-B kinase subunit beta in PDB entry 4kik, assembly 1, front view.
Inhibitor of nuclear factor kappa-B kinase subunit beta in PDB entry 4kik, assembly 1, side view.
Inhibitor of nuclear factor kappa-B kinase subunit beta in PDB entry 4kik, assembly 1, top view.
Molecule details ›

Search similar proteins

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