Assemblies
Assembly Name:
Major prion protein and IG-heavy chain
Multimeric state:
hetero dimer
Accessible surface area:
11531.39 Å2
Buried surface area:
1257.48 Å2
Dissociation area:
628.74
Å2
Dissociation energy (ΔGdiss):
-2.85
kcal/mol
Dissociation entropy (TΔSdiss):
10.91
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-208987
Macromolecules
Chain: A
Length: 241 amino acids
Theoretical weight: 26.2 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam: Prion/Doppel alpha-helical domain
InterPro:
Length: 241 amino acids
Theoretical weight: 26.2 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P04156 (Residues: 24-231; Coverage: 90%)
Pfam: Prion/Doppel alpha-helical domain
InterPro:
Chain: B
Length: 130 amino acids
Theoretical weight: 14.28 KDa
Source organism: Lama glama
Expression system: Escherichia coli
Length: 130 amino acids
Theoretical weight: 14.28 KDa
Source organism: Lama glama
Expression system: Escherichia coli
- Immunoglobulin-like fold
- Immunoglobulin-like domain superfamily
- Immunoglobulin domain subtype
- Immunoglobulin V-set domain
- Immunoglobulin-like domain