Assemblies
Assembly Name:
Isocitrate dehydrogenase [NADP] cytoplasmic
Multimeric state:
homo dimer
Accessible surface area:
30658.27 Å2
Buried surface area:
11194.41 Å2
Dissociation area:
4,076.53
Å2
Dissociation energy (ΔGdiss):
61.23
kcal/mol
Dissociation entropy (TΔSdiss):
15.14
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-131150
Assembly Name:
Isocitrate dehydrogenase [NADP] cytoplasmic
Multimeric state:
homo dimer
Accessible surface area:
29888.97 Å2
Buried surface area:
11263.5 Å2
Dissociation area:
4,191.92
Å2
Dissociation energy (ΔGdiss):
58.13
kcal/mol
Dissociation entropy (TΔSdiss):
15.16
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-131150
Macromolecules
Chains: A, B, C
Length: 425 amino acids
Theoretical weight: 48.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam: Isocitrate/isopropylmalate dehydrogenase
InterPro:
Length: 425 amino acids
Theoretical weight: 48.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: O75874 (Residues: 1-414; Coverage: 100%)
Pfam: Isocitrate/isopropylmalate dehydrogenase
InterPro:
- Isocitrate dehydrogenase NADP-dependent
- Isopropylmalate dehydrogenase-like domain
- Isocitrate/isopropylmalate dehydrogenase, conserved site