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Structure of the carbohydrate-recognition domain of the C-type lectin mincle bound to trehalose

X-ray diffraction
1.4Å resolution
PDB entry 4kzv coloured by chain, front view.
PDB entry 4kzv coloured by chain, side view.
PDB entry 4kzv coloured by chain, top view.
Source organism: Bos taurus
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: C-type lectin domain-containing protein
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Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-122748
Assembly 2
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Assembly Name: C-type lectin domain-containing protein
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Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-122748

Macromolecules

C-type lectin domain-containing protein
Chains: A, B
Length: 134 amino acids
Theoretical weight: 15.74 KDa
Source organism: Bos taurus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: E1BHM0 (Residues: 79-211; Coverage: 63%)
Gene name: CLEC4E
Pfam: Lectin C-type domain
InterPro:
CATH: Mannose-Binding Protein A, subunit A
C-type lectin domain-containing protein in PDB entry 4kzv, assembly 1, front view.
C-type lectin domain-containing protein in PDB entry 4kzv, assembly 1, side view.
C-type lectin domain-containing protein in PDB entry 4kzv, assembly 1, top view.
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