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Crystal structure of TBL1XR1 WD40 repeats

X-ray diffraction
2.28Å resolution
PDB entry 4lg9 coloured by chain, front view.
PDB entry 4lg9 coloured by chain, side view.
PDB entry 4lg9 coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: F-box-like/WD repeat-containing protein TBL1XR1
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Multimeric state: monomeric
Accessible surface area: 14736.68 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-189861
Monomeric assembly 1 of PDB entry 4lg9 coloured by chemically distinct molecules, front view.
Monomeric assembly 1 of PDB entry 4lg9 coloured by chemically distinct molecules, side view.
Monomeric assembly 1 of PDB entry 4lg9 coloured by chemically distinct molecules, top view.
    Assembly 1
Confidence : 95%
No. subunits : 1
Symmetry : None
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3DComplex & QSbio predictionx
No. subunits : 1
Symmetry : None
Evidence : This biological assembly agrees with the prediction of both PISA & EPPIC

Macromolecules

F-box-like/WD repeat-containing protein TBL1XR1
Chain: A
Length: 400 amino acids
Theoretical weight: 43.65 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9BZK7 (Residues: 134-514; Coverage: 74%)
Gene names: IRA1, TBL1XR1, TBLR1
Pfam: WD domain, G-beta repeat
InterPro:
CATH: YVTN repeat-like/Quinoprotein amine dehydrogenase
F-box-like/WD repeat-containing protein TBL1XR1 in PDB entry 4lg9, assembly 1, front view.
F-box-like/WD repeat-containing protein TBL1XR1 in PDB entry 4lg9, assembly 1, side view.
F-box-like/WD repeat-containing protein TBL1XR1 in PDB entry 4lg9, assembly 1, top view.
PDBe-KB: UniProt Coverage View: Q9BZK7  
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