4m8l

X-ray diffraction
2.37Å resolution

crystal structure of RpiA-R5P complex

Released:
Model geometry
Fit model/data
Source organism: Francisella tularensis
Entry authors: Rostankowski R, Borek D, Orlikowska M, Nakka C, Grimshaw S, Otwinowski Z, Center for Structural Genomics of Infectious Diseases (CSGID)

Function and Biology Details

Reaction catalysed:
D-ribose 5-phosphate = D-ribulose 5-phosphate
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-107355 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribose-5-phosphate isomerase A Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 224 amino acids
Theoretical weight: 24.49 KDa
Source organism: Francisella tularensis
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
  • Canonical: A4IYN5 (Residues: 1-224; Coverage: 100%)
Gene names: FTW_1255, rpiA
Sequence domains: Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
Structure domains:

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 19-ID
Spacegroup: C2
Unit cell:
a: 168.203Å b: 151.958Å c: 36.29Å
α: 90° β: 93.98° γ: 90°
R-values:
R R work R free
0.239 0.238 0.274
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'