Structure analysis

Extended-Synaptotagmin 2, C2A- and C2B-domains, calcium bound

X-ray diffraction
2.552Å resolution
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: monomeric
Accessible surface area: 14385.7 Å2
Buried surface area: 263.23 Å2
Dissociation area: 41.63 Å2
Dissociation energy (ΔGdiss): 9.54 kcal/mol
Dissociation entropy (TΔSdiss): 0.05 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-106072

Macromolecules

Chain: A
Length: 299 amino acids
Theoretical weight: 34.27 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A0FGR8 (Residues: 363-660; Coverage: 32%)
Gene names: ESYT2, FAM62B, KIAA1228
Pfam: C2 domain
InterPro:
CATH: C2 domain

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