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Mus Musculus LTC4 synthase in apo form

X-ray diffraction
2.7Å resolution
PDB entry 4nta coloured by chain, front view.
PDB entry 4nta coloured by chain, side view.
PDB entry 4nta coloured by chain, top view.
Source organism: Mus musculus
Assembly composition:
homo trimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Leukotriene C4 synthase
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Multimeric state: homo trimer
Accessible surface area: 22252.67 Å2
Buried surface area: 11995.58 Å2
Dissociation area: 3,663.63 Å2
Dissociation energy (ΔGdiss): 40.21 kcal/mol
Dissociation entropy (TΔSdiss): 26.19 kcal/mol
Symmetry number: 3
PDBe Complex ID: PDB-CPX-178826

Macromolecules

Leukotriene C4 synthase
Chain: A
Length: 156 amino acids
Theoretical weight: 17.66 KDa
Source organism: Mus musculus
Expression system: Komagataella pastoris
UniProt:
  • Canonical: Q60860 (Residues: 2-150; Coverage: 99%)
Gene name: Ltc4s
Pfam: MAPEG family
InterPro:
CATH: Membrane associated eicosanoid/glutathione metabolism-like domain
Leukotriene C4 synthase in PDB entry 4nta, assembly 1, front view.
Leukotriene C4 synthase in PDB entry 4nta, assembly 1, side view.
Leukotriene C4 synthase in PDB entry 4nta, assembly 1, top view.
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