› 4nxj

X-ray diffraction
2.18Å resolution

Crystal Structure of PF3D7_1475600, a bromodomain from Plasmodium Falciparum

Released:
DOI: 10.2210/pdb4nxj/pdb
PDB entry 4nxj coloured by chain, front view.
PDB entry 4nxj coloured by chain, side view.
PDB entry 4nxj coloured by chain, top view.
Source organism: Plasmodium falciparum 3D7
Entry authors: Wernimont AK, Loppnau P, Knapp S, Fonseca M, Brennan PE, Dong A, Walker JR, Arrowsmith CH, Edwards AM, Bountra C, Hui R, Hutchinson A, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184806 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bromo domain-containing protein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 119 amino acids
Theoretical weight: 14.43 KDa
Source organism: Plasmodium falciparum 3D7
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8IK82 (Residues: 8-125; Coverage: 16%)
Gene name: PF3D7_1475600
Sequence domains: Bromodomain
Structure domains: Bromodomain-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E+ SUPERBRIGHT
Spacegroup: P21
Unit cell:
a: 41.24Å b: 41.352Å c: 107.432Å
α: 90° β: 93.37° γ: 90°
R-values:
R R work R free
0.205 0.203 0.25
Expression system: Escherichia coli

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