Function and Biology Details
Reaction catalysed:
ATP + 5'-dephospho-DNA = ADP + 5'-phospho-DNA
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- P-loop containing nucleoside triphosphate hydrolase
- Pcf11, Clp1-ID
- Clp1, C-terminal domain superfamily
- Pre-mRNA cleavage complex subunit Clp1, C-terminal
- Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain
- Clp1, N-terminal beta-sandwich domain
- Polyribonucleotide 5-hydroxyl-kinase Clp1
- Clp1, N-terminal beta-sandwich domain superfamily
1 more domain
Structure analysis Details
Assemblies composition:
Assembly name:
PDBe Complex ID:
PDB-CPX-153823 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
mRNA cleavage and polyadenylation factor CLP1
Molecule details ›
Chains: A, C
Length: 453 amino acids
Theoretical weight: 51.31 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Length: 453 amino acids
Theoretical weight: 51.31 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q08685 (Residues: 1-445; Coverage: 100%)
Sequence domains:
- N-terminal beta-sandwich domain of polyadenylation factor
- mRNA cleavage and polyadenylation factor CLP1 P-loop
- Pre-mRNA cleavage complex II protein Clp1
Protein PCF11
Molecule details ›
Chains: B, D, U
Length: 115 amino acids
Theoretical weight: 12.83 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Pcf11, Clp1-interaction domain
Length: 115 amino acids
Theoretical weight: 12.83 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P39081 (Residues: 454-563; Coverage: 18%)
Sequence domains: Pcf11, Clp1-interaction domain
