Structure analysis

X-ray crystal structure of racemic non-glycosylated chemokine Ser-CCL1

X-ray diffraction
2Å resolution
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: homo dimer
Accessible surface area: 9333.37 Å2
Buried surface area: 5241.01 Å2
Dissociation area: 1,234.78 Å2
Dissociation energy (ΔGdiss): 32.11 kcal/mol
Dissociation entropy (TΔSdiss): 10.86 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-149609
Assembly 2
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Multimeric state: homo dimer
Accessible surface area: 9048.79 Å2
Buried surface area: 3953.06 Å2
Dissociation area: 934.76 Å2
Dissociation energy (ΔGdiss): 25.38 kcal/mol
Dissociation entropy (TΔSdiss): 10.57 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-219490

Macromolecules

Chains: A, B
Length: 74 amino acids
Theoretical weight: 8.59 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P22362 (Residues: 23-96; Coverage: 100%)
Gene names: CCL1, SCYA1
Pfam: Small cytokines (intecrine/chemokine), interleukin-8 like
InterPro:
CATH: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Search similar proteins

Chains: C, D
Length: 74 amino acids
Theoretical weight: 8.59 KDa
Source organism: synthetic construct
Expression system: Not provided
InterPro:

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