Structure analysis

Dehydratase domain of the polyketide PpsC from Mycobacterium tuberculosis

X-ray diffraction
2.7Å resolution
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: monomeric
Accessible surface area: 11769.21 Å2
Buried surface area: 269.01 Å2
Dissociation area: 134.51 Å2
Dissociation energy (ΔGdiss): 9.16 kcal/mol
Dissociation entropy (TΔSdiss): 0.65 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-161211

Macromolecules

Chain: A
Length: 325 amino acids
Theoretical weight: 34.46 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P96202 (Residues: 921-1222; Coverage: 14%)
Gene names: Rv2933, ppsC
Pfam:
InterPro:
CATH: Polyketide synthase dehydratase

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