EC 2.5.1.47: Cysteine synthase
Reaction catalysed:
O-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate
Systematic name:
O-acetyl-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase
Alternative Name(s):
- 3-O-acetyl-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase
- Acetylserine sulfhydrylase
- Cysteine synthetase
- O(3)-acetyl-L-serine acetate-lyase (adding hydrogen-sulfide)
- O(3)-acetyl-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase
- O-acetyl-L-serine sulfhydrylase
- O-acetyl-L-serine sulfohydrolase
- O-acetylserine (thiol)-lyase
- O-acetylserine (thiol)-lyase A
- O-acetylserine sulfhydrylase
- OAS sulfhydrylase
GO terms
Biochemical function:
Biological process:
Cellular component:
Sequence family
Protein family (Pfam)
![The deposited structure of PDB entry 4ore contains 1 copy of Pfam domain PF00291 (Pyridoxal-phosphate dependent enzyme) in Cysteine synthase. Showing 1 copy in chain A [auth X].](https://www.ebi.ac.uk/pdbe/static/entry/4ore_1_X_Pfam_PF00291_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>4ore</span> contains 1 copy of Pfam domain <span class='highlight'>PF00291 (Pyridoxal-phosphate dependent enzyme)</span> in <span class='highlight'>Cysteine synthase</span>. Showing 1 copy in chain <span class='highlight'>A [auth X]</span>.")
InterPro annotations
IPR036052
Domain description:
Tryptophan synthase beta chain-like, PALP domain superfamily
Occurring in:
Occurring in:
IPR001216
Domain description:
Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site
Occurring in:
Occurring in:
CATH domain![The deposited structure of PDB entry 4ore contains 2 copies of CATH domain 3.40.50.1100 (Rossmann fold) in Cysteine synthase. Showing 2 copies in chain A [auth X].](https://www.ebi.ac.uk/pdbe/static/entry/4ore_1_X_CATH_3.40.50.1100_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>4ore</span> contains 2 copies of CATH domain <span class='highlight'>3.40.50.1100 (Rossmann fold)</span> in <span class='highlight'>Cysteine synthase</span>. Showing 2 copies in chain <span class='highlight'>A [auth X]</span>.")