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Structure of rabbit skeletal muscle actin in complex with a hybrid peptide comprising thymosin beta4 and the lysine-rich region of Cordon-Bleu

Source organisms:
Biochemical function: protein binding
Biological process: mesenchyme migration
Cellular component: cytoskeleton

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF00022
Domain description: Actin
Occurring in:
  1. Actin, alpha skeletal muscle
The deposited structure of PDB entry 4pl8 contains 2 copies of Pfam domain PF00022 (Actin) in Actin, alpha skeletal muscle. Showing 1 copy in chain A.

PF01290
Domain description: Thymosin beta-4 family
Occurring in:
  1. Protein cordon-bleu; Thymosin beta-4
The deposited structure of PDB entry 4pl8 contains 1 copy of Pfam domain PF01290 (Thymosin beta-4 family) in Protein cordon-bleu. Showing 1 copy in chain B [auth H].

InterPro InterPro annotations
IPR004000
Domain description: Actin family
Occurring in:
  1. Actin, alpha skeletal muscle
IPR001152
Domain description: Beta-thymosin
Occurring in:
  1. Protein cordon-bleu; Thymosin beta-4
IPR004001
Domain description: Actin, conserved site
Occurring in:
  1. Actin, alpha skeletal muscle
IPR043129
Domain description: ATPase, nucleotide binding domain
Occurring in:
  1. Actin, alpha skeletal muscle
IPR038386
Domain description: Beta-thymosin superfamily
Occurring in:
  1. Protein cordon-bleu; Thymosin beta-4
IPR020902
Domain description: Actin/actin-like conserved site
Occurring in:
  1. Actin, alpha skeletal muscle

Structure domains

CATH CATH domains
3.30.420.40
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Nucleotidyltransferase; domain 5
Homology: Nucleotidyltransferase; domain 5
Occurring in:
  1. Actin, alpha skeletal muscle
The deposited structure of PDB entry 4pl8 contains 4 copies of CATH domain 3.30.420.40 (Nucleotidyltransferase; domain 5) in Actin, alpha skeletal muscle. Showing 2 copies in chain A.
3.90.640.10
Class: Alpha Beta
Architecture: Alpha-Beta Complex
Topology: Actin; Chain A, domain 4
Homology: Actin; Chain A, domain 4
Occurring in:
  1. Actin, alpha skeletal muscle
The deposited structure of PDB entry 4pl8 contains 2 copies of CATH domain 3.90.640.10 (Actin; Chain A, domain 4) in Actin, alpha skeletal muscle. Showing 1 copy in chain A.

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