› › Structure analysis

Structure of rabbit skeletal muscle actin in complex with a hybrid peptide comprising thymosin beta4 and the lysine-rich region of Cordon-Bleu

X-ray diffraction
2Å resolution
PDB entry 4pl8 coloured by chain, front view.
PDB entry 4pl8 coloured by chain, side view.
PDB entry 4pl8 coloured by chain, top view.
Source organisms:
Assembly composition:
hetero trimer (preferred)
Entry contents: 2 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Actin, alpha skeletal muscle and Protein cordon-bleu, Thymosin beta-4
hide full assembly name
Multimeric state: hetero trimer
Accessible surface area: 29480.03 Å2
Buried surface area: 6621.2 Å2
Dissociation area: 1,254.77 Å2
Dissociation energy (ΔGdiss): 3.91 kcal/mol
Dissociation entropy (TΔSdiss): 13.58 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-130838

Macromolecules

Actin, alpha skeletal muscle
Chains: A, B
Length: 375 amino acids
Theoretical weight: 41.88 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P68135 (Residues: 3-377; Coverage: 100%)
Gene names: ACTA, ACTA1
Pfam: Actin
InterPro:
CATH:
Actin, alpha skeletal muscle in PDB entry 4pl8, assembly 1, front view.
Actin, alpha skeletal muscle in PDB entry 4pl8, assembly 1, side view.
Actin, alpha skeletal muscle in PDB entry 4pl8, assembly 1, top view.
Molecule details ›

Search similar proteins

Protein cordon-bleu; Thymosin beta-4
Chain: H
Length: 73 amino acids
Theoretical weight: 8.33 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: O75128 (Residues: 1092-1106; Coverage: 1%)
  • Canonical: P62328 (Residues: 2-44; Coverage: 98%)
    • nullnull
Gene names: COBL, KIAA0633, TB4X, THYB4, TMSB4, TMSB4X
Pfam: Thymosin beta-4 family
InterPro:
Protein cordon-bleu in PDB entry 4pl8, assembly 1, front view.
Protein cordon-bleu in PDB entry 4pl8, assembly 1, side view.
Protein cordon-bleu in PDB entry 4pl8, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links