Function and Biology

Crystal structure of D-lactate dehydrogenase with NAD+ from Lactobacillus jensenii

Source organism: Lactobacillus jensenii 1153
Biochemical function: NAD binding
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

InterPro InterPro annotations
IPR029753
Domain description: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site
Occurring in:
  1. 4-phosphoerythronate dehydrogenase
IPR006140
Domain description: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain
Occurring in:
  1. 4-phosphoerythronate dehydrogenase
IPR036291
Domain description: NAD(P)-binding domain superfamily
Occurring in:
  1. 4-phosphoerythronate dehydrogenase
IPR006139
Domain description: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
Occurring in:
  1. 4-phosphoerythronate dehydrogenase

Structure domain

CATH CATH domain
3.40.50.720
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: NAD(P)-binding Rossmann-like Domain
Occurring in:
  1. 4-phosphoerythronate dehydrogenase
The deposited structure of PDB entry 4prl contains 4 copies of CATH domain 3.40.50.720 (Rossmann fold) in 4-phosphoerythronate dehydrogenase. Showing 2 copies in chain A.