Assemblies
Assembly Name:
Non-receptor tyrosine-protein kinase TYK2
Multimeric state:
monomeric
Accessible surface area:
11790.69 Å2
Buried surface area:
408.38 Å2
Dissociation area:
69.23
Å2
Dissociation energy (ΔGdiss):
10.93
kcal/mol
Dissociation entropy (TΔSdiss):
0.57
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-151548
Assembly Name:
Non-receptor tyrosine-protein kinase TYK2
Multimeric state:
monomeric
Accessible surface area:
11351.16 Å2
Buried surface area:
563.92 Å2
Dissociation area:
72.17
Å2
Dissociation energy (ΔGdiss):
11.16
kcal/mol
Dissociation entropy (TΔSdiss):
0.58
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-151548
Assembly Name:
Non-receptor tyrosine-protein kinase TYK2
Multimeric state:
homo dimer
Accessible surface area:
21980.38 Å2
Buried surface area:
2133.76 Å2
Dissociation area:
567.3
Å2
Dissociation energy (ΔGdiss):
14.79
kcal/mol
Dissociation entropy (TΔSdiss):
12.83
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-151549
Macromolecules
Chains: A, B
Length: 317 amino acids
Theoretical weight: 35.5 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
UniProt:
Pfam: Protein tyrosine and serine/threonine kinase
InterPro:
Length: 317 amino acids
Theoretical weight: 35.5 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
UniProt:
- Canonical:
P29597 (Residues: 575-869; Coverage: 25%)
Pfam: Protein tyrosine and serine/threonine kinase
InterPro:
- Protein kinase-like domain superfamily
- Protein kinase domain
- Serine-threonine/tyrosine-protein kinase, catalytic domain
