Function and Biology

Crystal structure of full length YvoA in complex with palindromic operator DNA

Source organism: Bacillus subtilis subsp. subtilis str. 168
Biochemical function: DNA-binding transcription factor activity
Biological process: negative regulation of DNA-templated transcription
Cellular component: not assigned

Sequence families

Pfam Protein families (Pfam)
PF07702
Domain description: UTRA domain
Occurring in:
  1. HTH-type transcriptional repressor NagR
The deposited structure of PDB entry 4wwc contains 2 copies of Pfam domain PF07702 (UTRA domain) in HTH-type transcriptional repressor NagR. Showing 1 copy in chain B.

PF00392
Domain description: Bacterial regulatory proteins, gntR family
Occurring in:
  1. HTH-type transcriptional repressor NagR
The deposited structure of PDB entry 4wwc contains 2 copies of Pfam domain PF00392 (Bacterial regulatory proteins, gntR family) in HTH-type transcriptional repressor NagR. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR000524
Domain description: Transcription regulator HTH, GntR
Occurring in:
  1. HTH-type transcriptional repressor NagR
IPR011663
Domain description: UbiC transcription regulator-associated
Occurring in:
  1. HTH-type transcriptional repressor NagR
IPR028978
Domain description: Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily
Occurring in:
  1. HTH-type transcriptional repressor NagR
IPR036390
Domain description: Winged helix DNA-binding domain superfamily
Occurring in:
  1. HTH-type transcriptional repressor NagR
IPR036388
Domain description: Winged helix-like DNA-binding domain superfamily
Occurring in:
  1. HTH-type transcriptional repressor NagR

Structure domains

CATH CATH domains
3.40.1410.10
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Chorismate lyase
Homology: Chorismate lyase-like
Occurring in:
  1. HTH-type transcriptional repressor NagR
The deposited structure of PDB entry 4wwc contains 2 copies of CATH domain 3.40.1410.10 (Chorismate lyase) in HTH-type transcriptional repressor NagR. Showing 1 copy in chain B.
1.10.10.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Arc Repressor Mutant, subunit A
Homology: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Occurring in:
  1. HTH-type transcriptional repressor NagR
The deposited structure of PDB entry 4wwc contains 2 copies of CATH domain 1.10.10.10 (Arc Repressor Mutant, subunit A) in HTH-type transcriptional repressor NagR. Showing 1 copy in chain B.