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Crystal Structure of the coiled-coil surrounding Skip 1 of MYH7

X-ray diffraction
3.2Å resolution
PDB entry 4xa1 coloured by chain, front view.
PDB entry 4xa1 coloured by chain, side view.
PDB entry 4xa1 coloured by chain, top view.
Source organisms:
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Capsid assembly scaffolding protein, Microtubule-associated protein RP/EB family member 1, Myosin-7
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Multimeric state: homo dimer
Accessible surface area: 19590.59 Å2
Buried surface area: 7960.44 Å2
Dissociation area: 3,980.22 Å2
Dissociation energy (ΔGdiss): 67.81 kcal/mol
Dissociation entropy (TΔSdiss): 14.29 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-146358
Assembly 2
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Assembly Name: Capsid assembly scaffolding protein, Microtubule-associated protein RP/EB family member 1, Myosin-7
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Multimeric state: homo dimer
Accessible surface area: 18019.66 Å2
Buried surface area: 6419.64 Å2
Dissociation area: 3,209.82 Å2
Dissociation energy (ΔGdiss): 59.39 kcal/mol
Dissociation entropy (TΔSdiss): 13.61 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-146358

Macromolecules

Capsid assembly scaffolding protein; Microtubule-associated protein RP/EB family member 1; Myosin-7
Chains: A, B, C, D
Length: 159 amino acids
Theoretical weight: 18.45 KDa
Source organisms: Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P13848 (Residues: 1-49; Coverage: 50%)
  • Canonical: P12883 (Residues: 1173-1238; Coverage: 3%)
  • Canonical: Q15691 (Residues: 211-251; Coverage: 15%)
    • nullnullnull
Gene names: 7, MAPRE1, MYH7, MYHCB
Pfam:
InterPro:
Capsid assembly scaffolding protein in PDB entry 4xa1, assembly 1, front view.
Capsid assembly scaffolding protein in PDB entry 4xa1, assembly 1, side view.
Capsid assembly scaffolding protein in PDB entry 4xa1, assembly 1, top view.
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