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Crystal Structure of red flour beetle NR2E1/TLX

X-ray diffraction
2.6Å resolution
PDB entry 4xai coloured by chain, front view.
PDB entry 4xai coloured by chain, side view.
PDB entry 4xai coloured by chain, top view.
Source organisms:
Assembly composition:
hetero tetramer (preferred)
Entry contents: 2 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Maltose/maltodextrin-binding periplasmic protein, Tailless ortholog and Grunge, isoform J
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Multimeric state: hetero tetramer
Accessible surface area: 51597.52 Å2
Buried surface area: 6072.59 Å2
Dissociation area: 722.39 Å2
Dissociation energy (ΔGdiss): -0.68 kcal/mol
Dissociation entropy (TΔSdiss): 14.55 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-126065

Macromolecules

Maltose/maltodextrin-binding periplasmic protein; Tailless ortholog
Chains: A, B
Length: 573 amino acids
Theoretical weight: 63.65 KDa
Source organisms: Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P0AEY0 (Residues: 27-392; Coverage: 99%)
  • Canonical: Q9NCL0 (Residues: 196-396; Coverage: 50%)
    • nullnull
Gene names: ECs5017, Z5632, malE
Pfam:
InterPro:
Maltose/maltodextrin-binding periplasmic protein in PDB entry 4xai, assembly 1, front view.
Maltose/maltodextrin-binding periplasmic protein in PDB entry 4xai, assembly 1, side view.
Maltose/maltodextrin-binding periplasmic protein in PDB entry 4xai, assembly 1, top view.
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Grunge, isoform J
Chains: P, Q
Length: 21 amino acids
Theoretical weight: 2.4 KDa
Source organism: Drosophila melanogaster
Expression system: Not provided
UniProt:
  • Canonical: M9PHT1 (Residues: 1814-1834; Coverage: 1%)
Gene names: Atro, CG6964, Dmel\CG6964, Dmel_CG6964, GUG, Gug, atro, gug, l(3)01323, l(3)03928, l(3)S146907, l(3)j5A3, l(3)rO116
Grunge, isoform J in PDB entry 4xai, assembly 1, front view.
Grunge, isoform J in PDB entry 4xai, assembly 1, side view.
Grunge, isoform J in PDB entry 4xai, assembly 1, top view.
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