› › Structure analysis

X-ray crystal structure of Notch ligand Delta-like 1

X-ray diffraction
3.2Å resolution
PDB entry 4xbm coloured by chain, front view.
PDB entry 4xbm coloured by chain, side view.
PDB entry 4xbm coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1
Download    3D Visualisation
Assembly Name: Delta-like protein 1
hide full assembly name
Multimeric state: monomeric
Accessible surface area: 15032.94 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-126340
Monomeric assembly 1 of PDB entry 4xbm coloured by chemically distinct molecules, front view.
Monomeric assembly 1 of PDB entry 4xbm coloured by chemically distinct molecules, side view.
Monomeric assembly 1 of PDB entry 4xbm coloured by chemically distinct molecules, top view.
    Assembly 1
Confidence : 85%
No. subunits : 1
Symmetry : None
More details
3DComplex & QSbio predictionx
No. subunits : Unclear
Symmetry : Unclear
Evidence : This biological assembly agrees with the prediction of PISA but not of EPPIC
Assembly 2 (preferred)
Download    3D Visualisation
Assembly Name: Delta-like protein 1
hide full assembly name
Multimeric state: monomeric
Accessible surface area: 24443.5 Å2
Buried surface area: 222.78 Å2
Dissociation area: 111.39 Å2
Dissociation energy (ΔGdiss): -4.36 kcal/mol
Dissociation entropy (TΔSdiss): 1.95 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-126340
Monomeric assembly 2 of PDB entry 4xbm coloured by chemically distinct molecules, front view.
Monomeric assembly 2 of PDB entry 4xbm coloured by chemically distinct molecules, side view.
Monomeric assembly 2 of PDB entry 4xbm coloured by chemically distinct molecules, top view.
    Assembly 2
Confidence : 85%
No. subunits : 1
Symmetry : None
More details
3DComplex & QSbio predictionx
No. subunits : Unclear
Symmetry : Unclear
Evidence : This biological assembly agrees with the prediction of PISA but not of EPPIC

Macromolecules

Delta-like protein 1
Chains: A, B
Length: 531 amino acids
Theoretical weight: 57.43 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: O00548 (Residues: 21-545; Coverage: 74%)
  • Best match: O00548-2 (Residues: 21-223)
Gene names: DLL1, UNQ146/PRO172
Pfam:
InterPro:
CATH:
Delta-like protein 1 in PDB entry 4xbm, assembly 2, front view.
Delta-like protein 1 in PDB entry 4xbm, assembly 2, side view.
Delta-like protein 1 in PDB entry 4xbm, assembly 2, top view.
PDBe-KB: UniProt Coverage View: O00548  
153150100150200250300350400450500
 
200400
UniProt
O00548
Chains
Domains
Secondary structure
Flexibility predictions
Early folding residue predictions
Ligand binding sites
Sequence conservation
Variants
Molecule details ›

Search similar proteins

Quick links