Structure analysis

Glutathione S-transferase Omega 1 bound to covalent inhibitor C1-31

X-ray diffraction
1.94Å resolution
Source organism: Homo sapiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: homo dimer
Accessible surface area: 21026.92 Å2
Buried surface area: 2864.23 Å2
Dissociation area: 1,346.82 Å2
Dissociation energy (ΔGdiss): 2.48 kcal/mol
Dissociation entropy (TΔSdiss): 13.17 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-160265

Macromolecules

PDBe-KB: UniProt Coverage View: P78417  
124420406080100120140160180200220240
 
100200SNAMSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYGL
UniProt
P78417
Chains
Domains
Secondary structure
Flexibility predictions
Early folding residue predictions
Ligand binding sites
Interaction interfaces
Sequence conservation

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