Structure analysis

Coxsackievirus B3 Polymerase - F364Y mutant

X-ray diffraction
2.665Å resolution
Source organism: Coxsackievirus B3
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: monomeric
Accessible surface area: 21409.48 Å2
Buried surface area: 205.16 Å2
Dissociation area: 102.58 Å2
Dissociation energy (ΔGdiss): 17.15 kcal/mol
Dissociation entropy (TΔSdiss): 0.61 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-178362

Macromolecules

Chain: A
Length: 462 amino acids
Theoretical weight: 52.49 KDa
Source organism: Coxsackievirus B3
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5UEA2 (Residues: 1724-2185; Coverage: 21%)
Pfam: Viral RNA-dependent RNA polymerase
InterPro:
CATH:

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