› 5f4m

X-ray diffraction
2.27Å resolution

Protruding domain of GII.17 norovirus Kawasaki323

Released:
DOI: 10.2210/pdb5f4m/pdb
PDB entry 5f4m coloured by chain, front view.
PDB entry 5f4m coloured by chain, side view.
PDB entry 5f4m coloured by chain, top view.
Source organism: Norovirus 13-BH-1/2013/GII.17
Primary publication:
Structural Evolution of the Emerging 2014-2015 GII.17 Noroviruses.
Singh BK, Koromyslova A, Hefele L, Gürth C, Hansman GS
J Virol 90 2710-5 (2015)
PMID: 26699640

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-492906 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Capsid protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 308 amino acids
Theoretical weight: 34.09 KDa
Source organism: Norovirus 13-BH-1/2013/GII.17
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A0A0A7CJV4 (Residues: 225-528; Coverage: 57%)
Sequence domains: Calicivirus coat protein C-terminal
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand EDO 2 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P43212
Unit cell:
a: 121.51Å b: 121.51Å c: 156.6Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.161 0.159 0.187
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

4 review citations

Burden of acute gastroenteritis caused by norovirus in China: A systematic review.
Zhou et al. (2017)
3 more

4 mentions without citation

Nanobodies targeting norovirus capsid reveal functional epitopes and potential mechanisms of neutralization.
Koromyslova et al. (2017)
3 more