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Crystal structure of human SAMHD1 (amino acid residues 115-583) bound to ddGTP

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

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GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF01966
Domain description: HD domain
Occurring in:
  1. Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
The deposited structure of PDB entry 5ao1 contains 4 copies of Pfam domain PF01966 (HD domain) in Deoxynucleoside triphosphate triphosphohydrolase SAMHD1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR006674
Domain description: HD domain
Occurring in:
  1. Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
IPR003607
Domain description: HD/PDEase domain
Occurring in:
  1. Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

Structure domain

CATH CATH domain
1.10.3210.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Hypothetical protein af1432
Homology: Hypothetical protein af1432
Occurring in:
  1. Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
The deposited structure of PDB entry 5ao1 contains 4 copies of CATH domain 1.10.3210.10 (Hypothetical protein af1432) in Deoxynucleoside triphosphate triphosphohydrolase SAMHD1. Showing 1 copy in chain A.

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