› 5c2u

X-ray diffraction
1.55Å resolution

Ferredoxin-like domain of nucleoporin Nup54 bound to a nanobody

Released:
DOI: 10.2210/pdb5c2u/pdb
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PDB entry 5c2u coloured by chain, front view.
PDB entry 5c2u coloured by chain, side view.
PDB entry 5c2u coloured by chain, top view.
Source organisms:
Primary publication:
Crystal structure of the metazoan Nup62•Nup58•Nup54 nucleoporin complex.
Chug H, Trakhanov S, Hülsmann BB, Pleiner T, Görlich D
Science 350 106-10 (2015)
PMID: 26292704

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-207978 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Nanobody Chain: B
Molecule details ›
Chain: B
Length: 131 amino acids
Theoretical weight: 14.34 KDa
Source organism: Camelus dromedarius
Expression system: Escherichia coli
Structure domains: Immunoglobulins
Nucleoporin 54kDa S homeolog isoform X2 Chain: A
Molecule details ›
Chain: A
Length: 143 amino acids
Theoretical weight: 15.67 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
UniProt:
  • Canonical: K9ZTJ6 (Residues: 212-349; Coverage: 26%)
Gene names: nup54, nup54.S

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P3121
Unit cell:
a: 90.86Å b: 90.86Å c: 57.6Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.178 0.176 0.205
Expression system: Escherichia coli

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Citations

19 review citations

The nuclear pore complex: understanding its function through structural insight.
Beck et al. (2017)
18 more

3 mentions without citation

The Structure of the Nuclear Pore Complex (An Update).
Lin et al. (2019)
2 more

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