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Crystal structure of ABBA + UDP-C-Gal (long soak) + DI

X-ray diffraction
1.4Å resolution
PDB entry 5c3b coloured by chain, front view.
PDB entry 5c3b coloured by chain, side view.
PDB entry 5c3b coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form
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Multimeric state: homo dimer
Accessible surface area: 21703.51 Å2
Buried surface area: 5390.18 Å2
Dissociation area: 2,565.3 Å2
Dissociation energy (ΔGdiss): 26.69 kcal/mol
Dissociation entropy (TΔSdiss): 13.79 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-147726

Macromolecules

Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form
Chain: A
Length: 298 amino acids
Theoretical weight: 34.74 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P16442 (Residues: 64-354; Coverage: 82%)
Gene name: ABO
Pfam: Glycosyltransferase family 6
InterPro:
CATH: Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form in PDB entry 5c3b, assembly 1, front view.
Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form in PDB entry 5c3b, assembly 1, side view.
Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form in PDB entry 5c3b, assembly 1, top view.
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