Function and Biology

Human calpain PEF(S) with (2Z,2Z')-2,2'-disulfanediylbis(3-(6-iodoindol-3-yl)acrylic acid) bound

Source organism: Homo sapiens
Biochemical function: calcium ion binding
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

InterPro InterPro annotations
IPR002048
Domain description: EF-hand domain
Occurring in:
  1. Calpain small subunit 1
IPR018247
Domain description: EF-Hand 1, calcium-binding site
Occurring in:
  1. Calpain small subunit 1
IPR011992
Domain description: EF-hand domain pair
Occurring in:
  1. Calpain small subunit 1

Structure domain

CATH CATH domain
1.10.238.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Recoverin; domain 1
Homology: EF-hand
Occurring in:
  1. Calpain small subunit 1
The deposited structure of PDB entry 5d69 contains 2 copies of CATH domain 1.10.238.10 (Recoverin; domain 1) in Calpain small subunit 1. Showing 1 copy in chain A.