› › Structure analysis

Human calpain PEF(S) with (2Z,2Z')-2,2'-disulfanediylbis(3-(6-iodoindol-3-yl)acrylic acid) bound

X-ray diffraction
1.97Å resolution
PDB entry 5d69 coloured by chain, front view.
PDB entry 5d69 coloured by chain, side view.
PDB entry 5d69 coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Calpain small subunit 1
hide full assembly name
Multimeric state: homo dimer
Accessible surface area: 16631.06 Å2
Buried surface area: 5209.33 Å2
Dissociation area: 2,261.04 Å2
Dissociation energy (ΔGdiss): 29.26 kcal/mol
Dissociation entropy (TΔSdiss): 12.95 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-138097

Macromolecules

Calpain small subunit 1
Chains: A, B
Length: 173 amino acids
Theoretical weight: 20.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P04632 (Residues: 96-268; Coverage: 65%)
Gene names: CAPN4, CAPNS, CAPNS1
InterPro:
CATH: EF-hand
Calpain small subunit 1 in PDB entry 5d69, assembly 1, front view.
Calpain small subunit 1 in PDB entry 5d69, assembly 1, side view.
Calpain small subunit 1 in PDB entry 5d69, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links