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Oxidoreductase Fragment of Mouse QSOX1 in Complex with a FAb Fragment from an Antibody Targeting Mouse and Human QSOX1

Source organism: Mus musculus
Biochemical function: flavin-dependent sulfhydryl oxidase activity
Biological process: not assigned
Cellular component: not assigned

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EC 1.8.3.2: Thiol oxidase

Reaction catalysed:
2 R'C(R)SH + O(2) = R'C(R)S-S(R)CR' + H(2)O(2)
Systematic name:
Thiol:oxygen oxidoreductase
Alternative Name(s):
  • Sulfhydryl oxidase

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF18108
Domain description: QSOX Trx-like domain
Occurring in:
  1. Sulfhydryl oxidase 1
The deposited structure of PDB entry 5d96 contains 2 copies of Pfam domain PF18108 (QSOX Trx-like domain) in Sulfhydryl oxidase 1. Showing 1 copy in chain D [auth A].

PF00085
Domain description: Thioredoxin
Occurring in:
  1. Sulfhydryl oxidase 1
The deposited structure of PDB entry 5d96 contains 2 copies of Pfam domain PF00085 (Thioredoxin) in Sulfhydryl oxidase 1. Showing 1 copy in chain D [auth A].

InterPro InterPro annotations
IPR003597
Domain description: Immunoglobulin C1-set
Occurring in:
  1. Light chain of Fab fragment from an antibody targeting mouse and human QSOX1
  2. Heavy chain of Fab fragment from an antibody targeting mouse and human QSOX1
IPR013106
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. Light chain of Fab fragment from an antibody targeting mouse and human QSOX1
  2. Heavy chain of Fab fragment from an antibody targeting mouse and human QSOX1
IPR036179
Domain description: Immunoglobulin-like domain superfamily
Occurring in:
  1. Light chain of Fab fragment from an antibody targeting mouse and human QSOX1
  2. Heavy chain of Fab fragment from an antibody targeting mouse and human QSOX1
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. Light chain of Fab fragment from an antibody targeting mouse and human QSOX1
  2. Heavy chain of Fab fragment from an antibody targeting mouse and human QSOX1
IPR007110
Domain description: Immunoglobulin-like domain
Occurring in:
  1. Light chain of Fab fragment from an antibody targeting mouse and human QSOX1
  2. Heavy chain of Fab fragment from an antibody targeting mouse and human QSOX1
IPR003599
Domain description: Immunoglobulin domain subtype
Occurring in:
  1. Light chain of Fab fragment from an antibody targeting mouse and human QSOX1
  2. Heavy chain of Fab fragment from an antibody targeting mouse and human QSOX1
IPR013766
Domain description: Thioredoxin domain
Occurring in:
  1. Sulfhydryl oxidase 1
IPR003006
Domain description: Immunoglobulin/major histocompatibility complex, conserved site
Occurring in:
  1. Light chain of Fab fragment from an antibody targeting mouse and human QSOX1
IPR041269
Domain description: Sulfhydryl oxidase, Trx-like domain
Occurring in:
  1. Sulfhydryl oxidase 1
IPR036249
Domain description: Thioredoxin-like superfamily
Occurring in:
  1. Sulfhydryl oxidase 1
IPR039798
Domain description: Sulfhydryl oxidase
Occurring in:
  1. Sulfhydryl oxidase 1

Structure domains

CATH CATH domains
2.60.40.10
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Immunoglobulins
Occurring in:
  1. Light chain of Fab fragment from an antibody targeting mouse and human QSOX1
  2. Heavy chain of Fab fragment from an antibody targeting mouse and human QSOX1
The deposited structure of PDB entry 5d96 contains 4 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in Light chain of Fab fragment from an antibody targeting mouse and human QSOX1. Showing 2 copies in chain E [auth B].
The deposited structure of PDB entry 5d96 contains 4 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in Heavy chain of Fab fragment from an antibody targeting mouse and human QSOX1. Showing 2 copies in chain C [auth J].
3.40.30.10
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Glutaredoxin
Homology: Glutaredoxin
Occurring in:
  1. Sulfhydryl oxidase 1
The deposited structure of PDB entry 5d96 contains 4 copies of CATH domain 3.40.30.10 (Glutaredoxin) in Sulfhydryl oxidase 1. Showing 2 copies in chain D [auth A].

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