Function and Biology

Ketosynthase from module 6 of the bacillaene synthase from Bacillus subtilis 168 (C167S mutant, crystal form 2)

Source organism: Bacillus subtilis subsp. subtilis str. 168
Biochemical function: acyltransferase activity
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF22336
Domain description: RhiE-like, KS-MAT linker domain
Occurring in:
  1. Polyketide synthase PksL

PF02801
Domain description: Beta-ketoacyl synthase, C-terminal domain
Occurring in:
  1. Polyketide synthase PksL
The deposited structure of PDB entry 5e6k contains 2 copies of Pfam domain PF02801 (Beta-ketoacyl synthase, C-terminal domain) in Polyketide synthase PksL. Showing 1 copy in chain B.

PF00109
Domain description: Beta-ketoacyl synthase, N-terminal domain
Occurring in:
  1. Polyketide synthase PksL
The deposited structure of PDB entry 5e6k contains 2 copies of Pfam domain PF00109 (Beta-ketoacyl synthase, N-terminal domain) in Polyketide synthase PksL. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR020841
Domain description: Polyketide synthase, beta-ketoacyl synthase domain
Occurring in:
  1. Polyketide synthase PksL
IPR016039
Domain description: Thiolase-like
Occurring in:
  1. Polyketide synthase PksL
IPR032821
Domain description: Polyketide synthase, C-terminal extension
Occurring in:
  1. Polyketide synthase PksL
IPR014031
Domain description: Beta-ketoacyl synthase, C-terminal
Occurring in:
  1. Polyketide synthase PksL
IPR014030
Domain description: Beta-ketoacyl synthase-like, N-terminal
Occurring in:
  1. Polyketide synthase PksL
IPR036388
Domain description: Winged helix-like DNA-binding domain superfamily
Occurring in:
  1. Polyketide synthase PksL

Structure domain

CATH CATH domain
3.40.47.10
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Peroxisomal Thiolase; Chain A, domain 1
Homology: Peroxisomal Thiolase; Chain A, domain 1
Occurring in:
  1. Polyketide synthase PksL
The deposited structure of PDB entry 5e6k contains 2 copies of CATH domain 3.40.47.10 (Peroxisomal Thiolase; Chain A, domain 1) in Polyketide synthase PksL. Showing 1 copy in chain B.